Anticholinergic Burden - Treatment Optimization

Status Completed

Clinical Trial Summary

There is increasing evidence that medications with anticholinergic effects may adversely affect cognitive function. Older adults are particularly sensitive to anticholinergic effects because of changes in pharmacokinetics and pharmacodynamics. The cumulative effect of taking one or more medicines with anticholinergic properties is referred to as anticholinergic burden. To estimate the anticholinergic burden, Boustani et al. published the Anticholinergic Cognitive Burden scale (2008). The objective of this study is to measure the association between the use of medications with anticholinergic properties (identified by the ACB scale) and cognitive performance. Anticholinergic use and cognitive performance will be measured at baseline and 6-months follow-up.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03208569
Study type	Observational
Source	Region Skane
Contact
Status	Completed
Phase
Start date	September 1, 2017
Completion date	September 30, 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05563805` - Exploring Virtual Reality Adventure Training Exergaming	N/A
Completed	`NCT03708692` - Menstrual Cycle Phases on Recovery and Cognitive Function
Active, not recruiting	`NCT04505345` - Virtual Reality Cognitive Training in Alcohol Use Disorder	N/A
Completed	`NCT04430465` - Effects of Wholegrains on Children's Health (KORN)	N/A
Completed	`NCT02915913` - Effects of Exercise Training on Cognitive Function and Neurotrophic Factors in Overweight Adults	N/A
Completed	`NCT01410097` - Physical and Cognitive Function - Look AHEAD Ancillary Study	N/A
Completed	`NCT03826121` - Efficacy and Safety of Sesame Oil Cake Extract on Improvement of Cognitive Function	N/A
Recruiting	`NCT05621278` - The Longitudinal Study of Mental Health in Child to Adult
Completed	`NCT05498415` - Feasibility, Acceptability, and Efficacy of the Sleep Move Stand Study	N/A
Completed	`NCT03793777` - The Effect of Aronia Melanocarpa Extract on Cognitive Function	N/A
Recruiting	`NCT05525299` - Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors	N/A
Completed	`NCT03698123` - Performance Nutrition for Residents and Fellows	N/A
Completed	`NCT04543500` - Self-regulation of Prefrontal Cortex During Emotional Cognitive Control	N/A
Recruiting	`NCT05891977` - Effect of Tomato Paste Consumption on the Microbiota-gut-brain Axis in Healthy Adults	N/A
Recruiting	`NCT05591885` - Nutrilite Memory Builder on the Improvement of Cognitive Function	N/A
Active, not recruiting	`NCT05575752` - Acute Health Effects of High Temperature Exposure	N/A
Completed	`NCT03716609` - Effects of Magnesium Supplementation on Hemodynamic Parameters and Cognitive Function	N/A
Completed	`NCT02763514` - The Effects of DHA- and EPA-enriched Oils on Cognitive Function and Mood	N/A
Completed	`NCT02675621` - Investigation of Acute Mood and Cognitive Performance Effects of Beverages Containing Phenolics in Healthy Adults	N/A
Completed	`NCT02344056` - Cognition Intervention Study Dortmund- Continued (Coco)	N/A