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NCT00087750 Clinical Trial

Interaction Between Cocaine and Quetiapine - 1

Cocaine-Related Disorders Clinical Trial

Official title:
Interaction Between IV Cocaine and Quetiapine

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00087750
Other study ID # NIDA-MDS-0001-1
Secondary ID
Status Active, not recruiting
Phase Phase 1
First received July 13, 2004
Last updated January 10, 2017
Start date October 2003

Study information
Verified date March 2005
Source National Institute on Drug Abuse (NIDA)
Contact n/a
Is FDA regulated No
Health authority United States: Food and Drug Administration
Study type Interventional

Clinical Trial Summary

The purpose of this study is to assess the safety of intravenous (IV) cocaine in subjects taking quetiapine at 3 dosage levels.

Description:

A placebo-controlled, double-blind, inpatient assessment of interaction between intravenous cocaine and quetiapine (seroquel) in cocaine-experienced subjects. To assess the safety of IV cocaine in subjects taking quetiapine at 3 dosage levels.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 12
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender All
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria:

Includes but is not limited to: non-treatment seeking individuals. Must meet DSM-IV criteria for cocaine abuse or dependence. Must be able to verbalize understanding of consent and provide written informed consent and verbalize willingness to complete study procedures. Site will provide further details.

Exclusion Criteria:

Please contact site for further information

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Quetiapine

Locations
Country Name City State
United States Boston University Medical Center Boston Massachusetts

Sponsors (1)
Lead Sponsor Collaborator
National Institute on Drug Abuse (NIDA)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Adverse events
Primary pharmacokinetic assessment
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