Clinical Trials Logo
  1. Home
  2. Chronic Stroke
  3. NCT03947645

Intensive Neurorehabilitation and Stimulation in Chronic Stroke Patients

Chronic Stroke Clinical Trial

Official title:
Intensive Neurorehabilitation and Stimulation in Chronic Stroke Patients With Severe Motor Impairment of the Upper Extremity

Clinical Trial Summary

Chronic stroke patients (> 6 months) with severe motor impairment of the upper extremity will be enrolled in this single-centre, randomized controlled clinical trial (RCT). All patients will take part in two blocks of high-intense motor training with concurrent neuromuscular stimulation of the paretic upper extremity. In a randomized, cross-over block design, patients will receive transcranial stimulation of either the ipsi- or contralesional hemisphere.

Clinical Trial Description

Chronic stroke patients (> 6 months) with severe motor impairment of the upper extremity and non-proportional recovery will be enrolled in this single-centre, randomized controlled clinical trial (RCT). All patients will take part in two blocks of high-intense motor training with concurrent neuromuscular stimulation of the paretic upper extremity. In a randomized, cross-over block design, patients will receive transcranial stimulation of either the ipsi- or contralesional hemisphere. The primary outcome measure is the Fugl-Meyer Assessment for upper extremity (FM-UE), acquired at baseline, after the intervention period, and at 3 months follow-up. Secondary outcome measures consist of further clinical parameters and biomarkers of corticospinal connectivity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03947645
Study type Interventional
Source University Hospital Tuebingen
Contact
Status Active, not recruiting
Phase N/A
Start date May 2, 2019
Completion date December 1, 2022
View Details
See also
  Status Clinical Trial Phase
Completed NCT03780296 - Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke N/A
Not yet recruiting NCT06057584 - Effect of Somatosensory Motor Intergration Training on Post-stroke Upper Limb Function. N/A
Completed NCT03228264 - A Trial Investigating Telerehabilitation as an add-on to Face-to-face Speech and Language Therapy in Post-stroke Aphasia. N/A
Completed NCT03531567 - Game-Based Home Exercise Programs in Chronic Stroke: A Feasibility Study N/A
Completed NCT02364232 - Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation N/A
Completed NCT04121754 - Post-Stroke Walking Speed and Community Ambulation Conversion Study N/A
Completed NCT04574687 - Effects of Action Observation Therapy on Fine Motor Skills of Upper Limb Functions in Chronic Stroke Patients. N/A
Recruiting NCT04534556 - Wireless Nerve Stimulation Device To Enhance Recovery After Stroke N/A
Recruiting NCT04974840 - Thera-band Resisted Treadmill Training for Chronic Stroke Patients N/A
Completed NCT04553198 - Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery N/A
Completed NCT04226417 - Effect of Home Based Transcranial Direct Current Stimulation (tDCS) With Exercise on Upper and Lower Limb Motor Functions in Chronic Stroke N/A
Recruiting NCT06049849 - Can Patients With Chronic Stroke Regain Living Independence by Daily Energizing With Biophoton Generators N/A
Active, not recruiting NCT02881736 - Proprioceptive Deficits and Anomalies in Movement-error Processing in Chronic Stroke Patients N/A
Completed NCT03208634 - Rehabilitation Multi Sensory Room for Robot Assisted Functional Movements in Upper-limb Rehabilitation in Chronic Stroke N/A
Completed NCT05183100 - Effects of Neurodynamics on Lower Extremity Spasticity - a Study in Chronic Stroke N/A
Completed NCT03326349 - Home-based Computerized Cognitive Rehabilitation in Chronic Stage Stroke N/A
Recruiting NCT04721860 - Optimizing Training in Severe Post-Stroke Walking Impairment N/A
Recruiting NCT06051539 - Outcomes and Health Economics of Stroke Using Rhythmic Auditory Stimulation N/A
Not yet recruiting NCT06060470 - Active Balance and Cardio Care Intervention on Physical and Cardiovascular Health in People With Chronic Stroke N/A
Recruiting NCT05591196 - Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke N/A