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Chronic Stroke clinical trials

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NCT ID: NCT06191406 Recruiting - Chronic Stroke Clinical Trials

Five-year Changes in Patients With Chronic Stroke

Start date: November 1, 2023
Phase:
Study type: Observational

Objective of the study: - To determine changes in physical and cognitive function in patients with chronic stroke over 5 years - To determine whether there are differences in physical and cognitive function in chronic stroke patients with different baseline levels of physical activity

NCT ID: NCT06134921 Recruiting - Ischemic Stroke Clinical Trials

Effects of Transcranial Electrical Stimulation in Stroke Individuals

Start date: November 15, 2023
Phase: N/A
Study type: Interventional

The present study will use transcranial electrical stimulation (tES) with conventional physical therapy in sub-acute (at least 2 weeks after stroke onset) to chronic stroke within 2 years to investigate the effect on cortical activity and upper and lower limb motor function. The findings may support the usage of tES for improving brain activity and motor function in a clinic setting.

NCT ID: NCT06131827 Recruiting - Chronic Stroke Clinical Trials

Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.

Start date: July 17, 2023
Phase: N/A
Study type: Interventional

Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb dysfunction. In this study we use two techniques to improve upper limb motor dysfunction and reduce spasticity. One is task-based activities which is used to improve motor function and focus on active participation rather than normal movement pattern and other is neural mobilization which aims to reduce spasticity which is most common in stroke patients.

NCT ID: NCT06116942 Recruiting - Chronic Stroke Clinical Trials

Magnetic Brain Stimulation and Computer-based Motor Training for Rehabilitation After Stroke

Start date: November 8, 2023
Phase: N/A
Study type: Interventional

The goal of the present clinical trial is to explore whether an innovative technology-based approach can help individuals who have had a stroke and can no longer move their hands with ease. Our approach consists of a combination of two technologies: Transcranial Magnetic Stimulation (TMS) and a Brain-Computer Interface (BCI). The former entails the application of magnetic fields over the head to stimulate the brain preparing it for a better ability to produce movement. The latter consists of measuring brain activity to personalize a type of computer-based training that is designed to increase communication between the brain and the muscles.

NCT ID: NCT06113965 Recruiting - Stroke Clinical Trials

Neural Operant Conditioning

Start date: May 31, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient. The main questions it aims to answer are: - Can participants self-regulate reflex excitability - Can participants self-regulate reflex, reduce spasticity and improve walking Participants will undergo surface stimulation to evoke spinal reflexes and will be asked to control these reflexes therefore reducing spasticity. Researchers will compare result to able bodied participants to see if [insert effects]

NCT ID: NCT06051539 Recruiting - Chronic Stroke Clinical Trials

Outcomes and Health Economics of Stroke Using Rhythmic Auditory Stimulation

OrcHESTRAS
Start date: October 10, 2023
Phase: N/A
Study type: Interventional

The purpose of this trial is to assess engagement, efficacy, durability, and impact on health care resource utilization of MR-001 in persons with chronic stroke who have a gait deficit after in-home/community use.

NCT ID: NCT06049849 Recruiting - Chronic Stroke Clinical Trials

Can Patients With Chronic Stroke Regain Living Independence by Daily Energizing With Biophoton Generators

Start date: October 31, 2023
Phase: N/A
Study type: Interventional

Study objective The purpose of this clinical research is to verify if the patient with chronic stroke can regain the ability of living independently after daily using Testa BioHealing® Biophoton Generators to increase the energy of the brain and other parts of the body. Study design This study is a randomized, triple-blinded, placebo-controlled prospective intervention clinical research. At least 46 patients with chronic stroke will participate in the live-in observational study in a Tesla MedBed Center. Study patient population The adult patient with a chronic stroke which was defined as a stroke occurred at least 6 months ago with a significant disability unable to have an independent life, is to be considered as a qualified participant.

NCT ID: NCT05962060 Recruiting - Chronic Stroke Clinical Trials

PNF With and Without EMS on Spasticity, Gait and Lower Limb Function in Chronic Stroke Patients

Start date: November 17, 2022
Phase: N/A
Study type: Interventional

The main purpose of conducting this study is to decrease the tone through PNF techniques and EMS application. By decreasing the tone, spasticity may be reduced in stroke patients and may inturn lead to better approaches to treat those patients. So, the findings of this study can help in formulation of future guidelines for management of stroke that will help the clinicians to treat such patients in more efficient way..

NCT ID: NCT05953415 Recruiting - Clinical trials for Cognitive Impairment

pBFS-guided iTBS Over the Left DLPFC for Chronic PSCI

Start date: August 18, 2023
Phase: N/A
Study type: Interventional

The study aims to investigate the efficacy and safety of intermittent theta burst stimulation (iTBS) guided by the personalized Brain Functional Sector (pBFS) technique in the treatment of patients with chronic post-stroke cognitive impairment.

NCT ID: NCT05947318 Recruiting - Rehabilitation Clinical Trials

Effect of tACS on the Recovery of Motor Control of the Upper Limb and Cerebral Connectivity in Chronic Stroke Patients

tACS
Start date: May 2, 2023
Phase: N/A
Study type: Interventional

This project seeks to evaluate the effect of transcranial alternating current stimulation (tACS) on the recovery of motor control of the upper limb and associated neuronal synchrony during a 14-sessions (5-week) rehabilitation program for adult patients with diagnosis of stroke at chronic stage. Specifically, the stimulation on Gamma ranges, because the evidence available so far allows us to propose that the tACS in the Gamma range (around 70 Hz) facilitates motor execution. For this purpose, the experimental approach involves active (70 Hz in Gamma rhythm and 7 Hz, Theta rhythm) and sham tACS together with an analytical and integrated motor training with a double-blind and randomized design. Our hypothesis is that Gamma frequency tACS restores neuronal synchrony in Beta range, which enhances the upper limb motor recovery associated with a training program. Using specific motor control parameters, clinical scales and electroencephalography, the immediate and long-term (3 months after finished the training) behavioral and neurophysiological effect of this new neurostimulation paradigm (tACS plus training) for motor rehabilitation of stroke will be established.