Chronic Ischemic Heart Disease Clinical Trial
STable Coronary Artery Diseases RegisTry
Observational, prospective multicentric, national study, evaluating the diagnostic and therapeutic pathways of patient with cronic coronary artery disease followed in Italian cardiology centers.
Coronary heart disease is still highly prevalent in the world, and chronic stable angina is
one of the most common clinical presentations of this disease. The objectives of chronic
stable angina treatment include the reduction of symptoms, the inhibition or slowing of the
progression of the disease, the prevention of associated cardiovascular events such as
myocardial infarction, and the possible improvement of survival.The results of COURAGE Study
and of meta-analysis of more recent studies demonstrate that patients in optimized medical
therapy (OMT) (aspirin, beta-blocker and statin in association with an ACE-inhibitor and
strict control of risk factors). ) the percutaneous coronary revascularization procedure
(PCI) did not lead to an improvement in the cardiovascular prognosis. These data led the
groups in charge of drafting the guidelines to recommend OMT as an initial treatment of
stable angina, reserving the revascularization procedure for those patients with symptoms not
adequately controlled by medical therapy.
It is therefore considered appropriate to plan a registry in patients with stable coronary artery disease that has the ability to describe in the heterogeneity of Italian cardiological centers the current characteristics of these patients, their treatment modalities, adherence to the current guidelines both as regards invasive therapy that the optimized medical, the use and the total cost of the resources needed to manage this pathology, the clinical course one year after entering the register.
Consecutive patients discharged (after an ordinary or day hospital admission) or managed as outpatient at Cardiology department participating in the project with a diagnosis of stable coronary artery disease will be included in the register. Enrollment will last 3 months in each center, starting with the first enrolled patient, or up to 50 patients enrolled. ;
|Source||Heart Care Foundation|
|Start date||March 17, 2016|
|Completion date||April 24, 2018|
||Phase 1/Phase 2|
||Phase 1/Phase 2|
||Phase 2/Phase 3|