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Cholestasis clinical trials

View clinical trials related to Cholestasis.

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NCT ID: NCT01151280 Completed - Clinical trials for Anastomotic Biliary Stricture Post Orthotopic Liver Transplant

WallFlex Biliary Post Liver Transplant IDE Pilot

Start date: October 2009
Phase: N/A
Study type: Interventional

The primary objective of this study is to demonstrate effectiveness of the WallFlex Biliary RX Fully Covered Stent for anastomotic biliary strictures in post-orthotopic liver transplant (OLT) patients.

NCT ID: NCT01082419 Completed - Liver Cirrhosis Clinical Trials

Acoustic Radiation Force Impulse Imaging (ARFI) : a New Technique to Assess Liver Elasticity

NARFI
Start date: April 2010
Phase: N/A
Study type: Interventional

Liver stiffness measurement (LSM) by non invasive methods is increasingly used to estimate liver fibrosis in patients with chronic liver diseases. However, there is growing evidence that fibrosis is not the only determinant of liver stiffness. Indeed inflammation, cholestasis, congestion could also interfere with stiffness measurements. Acoustic radiation force impulse imaging (ARFI) is a new technology to perform real time LSM. Using a standard ultrasonographic probe, it offers elastography with a flexible metering box at variable depth, allowing the examination of specific area.

NCT ID: NCT01073202 Completed - Clinical trials for Liver Transplantation

Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation

Start date: May 2005
Phase: N/A
Study type: Interventional

This study is designed to investigate the possible beneficial effects of UDCA on liver graft recovery early after adult liver transplantation.

NCT ID: NCT01072721 Completed - Cystic Fibrosis Clinical Trials

Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis

PEDISCAN
Start date: January 19, 2010
Phase: N/A
Study type: Interventional

Early diagnosis of liver fibrosis is useful for the follow-up and treatment of chronic liver disease. At present, the unique validated method to evaluate the liver fibrosis in children, is the liver biopsy which is an invasive method. If the elastometry method is proved to be a good method to evaluate the fibrosis in children, a numerous liver biopsy could be avoided.

NCT ID: NCT01050660 Completed - Clinical trials for Parenteral Nutrition-Associated Liver Disease

Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates

Start date: June 2009
Phase: N/A
Study type: Interventional

The goal of the study is to determine if parenteral nutrition-associated cholestasis (PNAC) is related to the amount of parenteral (intravenous) fat administered to premature babies until full enteral nutrition is achieved.

NCT ID: NCT01014390 Completed - Biliary Stricture Clinical Trials

WallFlex Biliary Fully Covered (FC) Benign Stricture Study

Start date: December 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and performance of the WallFlex® Biliary RX Fully Covered Stent as a treatment of biliary obstruction resulting from benign bile duct strictures.

NCT ID: NCT00910104 Completed - Clinical trials for Short Bowel Syndrome

Cholestasis Reversal: Efficacy of IV Fish Oil

Reversal
Start date: September 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether Omegaven is effective in the treatment of parenteral nutrition associated liver disease (PNALD).

NCT ID: NCT00846963 Completed - Cholestasis Clinical Trials

Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in Neonates

URSONEONAT
Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine whether ursodiol is effective in the treatment of parenteral nutrition associated cholestasis in neonates.

NCT ID: NCT00826020 Completed - Cholestasis Clinical Trials

Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis

Start date: May 1, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if established parenteral nutrition (PN) associated liver disease can be reversed or its progression halted by using a parenteral fat emulsion prepared from fish oil as measured by normalization of serum levels of hepatic enzymes and bilirubin.

NCT ID: NCT00738101 Completed - Cholestasis Clinical Trials

Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in Infants

Start date: September 2008
Phase: N/A
Study type: Interventional

To provide a mechanism for critically ill infants with parenteral nutrition (PN) associated cholestasis to receive Omegaven for compassionate use situations for which there are no satisfactory alternative treatments.