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Comparison of Extra-Virgin and Refined Olive Oil on Some Cardiovascular Risk Factors

Cardiovascular Risk Factor Clinical Trial

Official title:
Comparison of Effects of Extra-virgin and Refined Olive Oil Consumption on Plasma Lipids and Inflammatory Markers in Patients Undergoing Coronary Angiography

Clinical Trial Summary

Consumption of extra-virgin olive oil has beneficial effects on cardiovascular risk factors. The purpose of this study is to compare the effects of extra-virgin olive oil and refined olive oil, in adjunct to conventional medical treatment, in improving liver enzymes, plasma lipid profile and inflammatory markers in patients with cardiovascular risk factors.

Clinical Trial Description

A randomized placebo controlled clinical trial will be conducted in Rajaie Cardiovascular Center in Tehran, Iran. After review of the inclusion and exclusion criteria and explanation of the design of the study, written consent form will be completed. The participants are 40 eligible patients, aged 20-75 years. Intervention group will be received 25 mL/d extra-virgin olive oil and control group will be received 25 mL/d refined olive oil for 6 weeks. Fasting blood sample will be taken to measure lipid profile, liver enzymes and inflammatory markers (Interleukine-6 [IL-6] and Interleukine-10 [IL-10] and C-Reactive Protein [CRP]). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03796780
Study type Interventional
Source Shahid Beheshti University
Contact
Status Completed
Phase N/A
Start date January 1, 2019
Completion date October 1, 2019
View Details
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