Cardiac Insufficiency Clinical Trial
Official title:
Time Course of Circulating Myocardial Biomarkers After a TASH Procedure.
The study evaluates the released myocardial substances in blood of HOCM patients after TASH procedure (small "controlled" myocardial infarction). This helps to identify new pathomechanisms and biomarker and thus provides a better understanding of development and progress of cardiac insufficiency.
All patients who receive a TASH procedure in the Medical Clinic I routinely receive routinely
implementation of arterial pressure catheter for invasive blood pressure monitoring (usually
Arteria radialis) as well as a central venous catheter. Directly after the procedure, the
blood is taken through the central venous catheter. The operation is then terminated as
planned.
The postoperative treatment is performed according to the Standard Operating Procedures
(SOPs) of the Medical clinic I -regular blood sampling is performed to monitor the patient's
cardiac, renal and hepatic lab values. The patient is released on the 3-5th post-operative
day.
As part of a routine outpatient visit to the Medical Clinic I 1 week and 1 month after the
TASH procedure, an anamnestic record as well as a blood analysis is made. One month after the
TASH procedure, an echocardiographic follow-up of the HOCM is routinely performed.
Adverse events or serious adverse events are documented, assessed and reported in accordance
with GCP (good clinical practice).
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