Carcinologic Ear, Nose, and Throat (ENT) Surgery Clinical Trial
Official title:
Intravenous Lidocaine in Carcinologic ENT Surgery: A Randomized Controlled Trial for Evaluation of Opioid Saving Strategy and Chronic Post-surgical Pain
Lidocaine, local anesthetic used for more than five decades, is being intravenously
administered aiming at managing pain in different types of surgeries with promising results.
Opioid-induced hyperalgesia need to be considered in ear-nose-throat (ENT) surgery owing to
the difficulty of locoregional anesthesia and high level of opioid consumption.
This randomized study aims to compare quality of perioperative analgesia after infusion of
intravenous lidocaine during carcinological ENT surgery. The main purpose of this study is to
evaluate morphine consumption during the 48 postoperative hours.
Others purposes are evaluation of peroperative remifentanil consumption, morphine consumption
during the 24 postoperative hours, chronic post-surgical pain evaluated from 3 to 6 months
after carcinologic ENT surgery, and incidence of side effects that can be attributed to
lidocaine infusion.
n/a