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Clinical Trial Summary

The purpose of this study is to find out what effects being re-treated with durvalumab has on cancer.

The researchers doing this study also want to evaluate if prednisone (a type of steroid), when given together with durvalumab, can reduce any side effects.


Clinical Trial Description

Durvalumab is a new type of drug for many types of cancer. Durvalumab is an immunotherapy drug and not a chemotherapy drug. Laboratory tests show that it works by allowing the immune system (PD-1 and PD-L1 interaction) to detect your cancer and reactivating the immune response. This may help to slow down the growth of cancer or may cause cancer cells to die. Durvalumab has been shown to shrink tumours in animals and has been studied in more than 6000 people. This drug seems promising but it is not clear if it can offer better results than standard treatment alone or if people can be re-treated with durvalumab after previous side effects ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03847649
Study type Interventional
Source Canadian Cancer Trials Group
Contact Martin Smoragiewicz
Phone 613-533-6430
Email msmoragiewicz@ctg.queensu.ca
Status Not yet recruiting
Phase Phase 2
Start date March 31, 2019
Completion date December 2022

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