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Clinical Trial Summary

This is a Phase II, non-randomized, open-label study to assess the efficacy, safety, and tolerability of dabrafenib and trametinib in stage IV disease to subjects with BRAF V600E mutant advanced non-small cell lung cancer. Subjects will receive dabrafenib 150 mg bid and trametinib 2 mg once daily in combination therapy and continue on treatment until disease progression, death, or unacceptable adverse event.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03543306
Study type Interventional
Source Asan Medical Center
Contact
Status Recruiting
Phase Phase 2
Start date June 30, 2018
Completion date June 30, 2022

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