Cancer Clinical Trial
Official title:
Individually Tailored Training Prescriptions in Cancer Patients: The TOP Study
The TOP Study is a two-stage study on individually tailored endurance and resistance training prescriptions for breast and prostate cancer patients after the end of primary therapy in order to optimize training effects.
The TOP Study is a two-stage study on individually tailored endurance and resistance training
prescriptions for breast and prostate cancer patients after the end of primary therapy in
order to optimize training effects.
The TOP Study Part I aims at identifying the most appropriate way of individual intensity
prescription. In a descriptive cross sectional study, 20 breast and 20 prostate cancer
patients perform singe endurance and resistance training sessions prescribed by means of
different methods of intensity prescription. The most appropriate method of intensity
prescription is identified through considering predictability/homogeneity of physiological
responses as well as perceived exertion and enjoyment.
The TOP Study Part II aims at investigating the most effective training method in terms of
enhancing physical fitness for both endurance and strength training. The design is an
exploratory four-arm 12-week randomized controlled training intervention trial in 60 breast
and 60 prostate cancer patients. In two endurance arms, vigorous continuous training is
compared to a polarized program consisting of moderate training and aerobic high intensity
interval training (HIIT). Similarly, in two resistance training arms, standard machine based
hypertrophy training is compared to training following a daily undulating periodization
design.
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