Breast Cancer Clinical Trial
Official title:
A Prospective, Randomized Comparison Between Paravertebral and Pectoral Nerve Block on Postoperative Pain, Persistent Post Surgical Pain and Cancer Recurrence After Mastectomy
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided
double space paravertebral block or a PECSII + parasternal block. In both groups, blocks will
be performed with 20 ml of ropivacaine 0.75%, plus ropivacaine 0.375% 10 ml for parasternal
block only.
Postoperative, all patients will receive a morphine PCA. They will follow at 6, 12, 24 months
for persistent postoperative surgical pain (PPSP) and cancer recurrence.
Patients scheduled for mastecotmy with or without axillary dissection, will be randomized to
receive preoperative either an ultrasound-guided double space paravertebral block or a PECSII
+ parasternal block. In both groups, blocks will be performed with 20 ml of ropivacaine
0.75%, plus ropivacaine 0.375% 10 ml for parasternal block only.
All the patients also received a general anesthesia induced by propofol and esmeron for
endotracheal intubation and desflurane for maintaining.
Sensory block by ice and pinprick test application and maximum spread after 40' from LA
injection will be registered.
Postoperative, all patients will receive a morphine PCA, ketorolac 30 mg/12h and paracetamol
1g each 8h.
Morphine consumption will be registered. Patients will follow at 6, 12, 24 months for
persistent postoperative surgical pain (PPSP) and cancer recurrence.
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