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Clinical Trial Summary

This research study is studying endostar in combination with chemotherapy as a possible treatment for HER-2 negative advanced breast cancer.


Clinical Trial Description

This is a multi-center phase II open label single-arm study to assess the safety and efficacy of endostar in combination with chemotherapy for patients with locoregionally recurrent or metastatic HER-2 negative breast cancer.

Endostar is an anti-angiogenesis drug. It is prepared by adding 9 amino acids to the N-terminal of the peptide chain on the basis of endostatin. Studies have shown that there may be a synergistic effect between endostar and chemotherapeutic agents. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03907098
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Xiaojia Wang, PhD
Phone 86 13906500190
Email wxiaojia0803@163.com
Status Recruiting
Phase Phase 2
Start date June 30, 2016
Completion date June 30, 2020

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