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Clinical Trial Summary

The goal of this study is to examine the role of Intraoperative Radiotherapy (IORT) in Ductal Carcinoma In-Situ (DCIS) and to improve the understanding of the clinical, radiographic, and patient-related impact of adopting IORT.


Clinical Trial Description

With advances in technology and screening, the overdiagnosis and overtreatment of ductal carcinoma in situ (DCIS) have increased. Minimizing treatment toxicity and cost is a high priority area of research. Intraoperative Radiation Therapy (IORT)is a form of radiation where a single high dose of irradiation is applied to the tumor bed at the time of lumpectomy. Its use has not been previously studied in DCIS. Proposed advantages include decreased toxicity to adjacent tissue and organs, reduction in healthcare costs, and improved quality of life. The investigators hypothesize that IORT is a safe and patient-friendly alternative to whole breast irradiation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03216421
Study type Interventional
Source Columbia University
Contact Eileen Connolly, MD
Phone 212-305-5050
Email epc2116@cumc.columbia.edu
Status Recruiting
Phase N/A
Start date September 12, 2017
Completion date December 31, 2019

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