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Brain Aneurysm clinical trials

View clinical trials related to Brain Aneurysm.

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NCT ID: NCT05626504 Active, not recruiting - Stroke Clinical Trials

Outcome Study of the Pipeline Embolization Device With Vantage Technology in Unruptured Aneurysms

PEDVU
Start date: October 27, 2022
Phase:
Study type: Observational

In this project the investigators study the safety and efficacy of the pipeline embolization device with vantage technology in treatment of unruptured brain aneurysms

NCT ID: NCT05317169 Recruiting - Brain Aneurysm Clinical Trials

Aneurysm Genetic Risk in Patients With QIB Changes

AnGen
Start date: December 12, 2018
Phase:
Study type: Observational

Intracranial aneurysm rupture is a leading cause of hemorrhagic strokes which carry high mortality and disability rates as well as high healthcare costs. Unruptured intracranial aneurysms (UIA) are common in the general population, occurring in 1-2% of individuals. Previous studies have shown that UIA growth and rupture are strongly associated with each other, with growing aneurysms 9-12 times more likely to rupture, and nearly all aneurysms growing prior to rupture. Thanks to advanced medical imaging, UIA are now more and more often detected incidentally. However not all aneurysms qualify for preventive surgical or interventional procedures according to current International Study of Unruptured Intracranial Aneurysms (ISUIA) guidelines, and some must therefore be monitored for growth. Current guidelines are based heavily on size, an inconsistent predictor of future growth. To improve management strategies for individual patients and more comprehensively assess aneurysm risk, the investigators propose to identify risk factors related to growth. Aneurysm etiology is multifactorial, with both genetic and environmental contributions to aneurysm formation, growth, and rupture. Exploring new risk factors based on aneurysm natural history and understanding the mechanisms underlying aneurysm rupture have been extensive research areas. As previous studies have shown that quantitative imaging biomarkers (QIB) can provide a more accurate assessment of the characteristics of aneurysms, the investigators propose a combined study which identifies QIB associated with aneurysm growth to identify factors related to growth.

NCT ID: NCT04553549 Completed - Stroke, Acute Clinical Trials

Safety and Feasibility of the Infinity Catheter for Radial Access

Start date: October 1, 2020
Phase:
Study type: Observational

The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial approach through a secondary use of the data collected during neurointerventional procedures. This includes evaluating the conversion rates to a transfemoral approach. A secondary aim of the study is to assess the radial artery occlusion rates post procedure.

NCT ID: NCT04439760 Completed - Brain Aneurysm Clinical Trials

Superior Cervical Ganglion Block, Transcranial Doppler

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess blood flow velocity in middle cerebral artery measured by transcranial doppler to determine the efficacy of SCG block in decreasing incidence or severity of vasospasm after MCA aneurysm surgery.

NCT ID: NCT03936647 Recruiting - Clinical trials for Intracranial Aneurysm

The RISE Trial: A Randomized Trial on Intra-Saccular Endobridge Devices

RISE
Start date: July 18, 2019
Phase: N/A
Study type: Interventional

Intracranial bifurcation aneurysms are commonly repaired with surgical and with endovascular techniques. Wide-necked bifurcation aneurysms (WNBA) are a difficult subset of aneurysms to successfully repair endovascularly, and a number of treatment adjuncts have been designed. One particularly promising innovation is the WEB (Woven EndoBridge), which permits placement of an intra-saccular flow diverting mesh across the aneurysm neck, but which does not require anti-platelet agent therapy. Currently, which treatment option leads to the best outcome for patients with WNBA remains unknown. There is a need to offer treatment with the WEB within the context of a randomized care trial, to patients currently presenting with aneurysms thought to be suitable for the WEB.

NCT ID: NCT03852680 Active, not recruiting - Brain Aneurysm Clinical Trials

Current Treatment Modalities for Wide Necked Intracranial Aneurysms

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

- Give an effective treatment for intracranial wide necked aneurysm and can detect the best method could be used. - Improve the outcome of these patients and decease rate of recurrence and complications.

NCT ID: NCT03844334 Completed - Brain Aneurysm Clinical Trials

CLinical EValuation of WEB 0.017 Device in Intracranial AneuRysms

CLEVER
Start date: March 21, 2019
Phase:
Study type: Observational

The study is an observational, European, multi-center, prospective assessment of the clinical utility of the 0.017 WEB Aneurysm Embolization System in subjects with intracranial aneurysms deemed appropriate for endovascular treatment.

NCT ID: NCT02687607 Completed - Brain Aneurysm Clinical Trials

CLARYS: CLinical Assessment of WEB® Device in Ruptured aneurYSms

CLARYS
Start date: January 2016
Phase:
Study type: Observational [Patient Registry]

An observational non-randomized, multi-center, prospective assessment of the clinical utility of the WEB Aneurysm Embolization System in subjects with ruptured intracranial aneurysms deemed appropriate for endovascular treatment. The population being treated in this Registry is a subset of the CE marked indication.

NCT ID: NCT02435823 Completed - Brain Aneurysm Clinical Trials

Safety Study of the PulseRider® in Patients Undergoing Treatment for Bifurcation Intracranial Aneurysms

AWARD
Start date: March 31, 2015
Phase: N/A
Study type: Interventional

This is a prospective multi-center, single arm, non-randomized study. It is designed to evaluate the safety of the PulseRider® in patients undergoing treatment for bifurcation intracranial aneurysms.

NCT ID: NCT02345395 Recruiting - Cerebral Aneurysm Clinical Trials

Safety Study of Minimally Invasive Approaches to Unruptured Anterior Circulation Aneurysms

MININCRUSP
Start date: September 2013
Phase: N/A
Study type: Interventional

The study is designed to evaluate the efficacy and safety of minimally invasive neurosurgical techniques for patients with incidental cerebral aneurysms of the anterior circulation in the Hospital das Clínicas of the University of São Paulo Medical School.