Autism Spectrum Disorder Clinical Trial
Official title:
The Hypothesis of Emotional Empathy Imbalance in Autism: Conscious and Non-conscious Processing of Emotional Faces
Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD)
should have a deficit of cognitive empathy and a surfeit of emotional empathy. Considering
that inconsistent amygdala reactivity to emotional faces might be ascribed to aberrant
attention in ASD, the investigators hypothesized to investigate if there would be an
imbalance between conscious and nonconscious emotional processing. This fMRI study recruited
26 youths and young adults with autism spectrum disorder and 25 matched controls, and
measured their amygdala reactivity and functional connectivity in response to conscious and
nonconscious (backward masked) perception of threatening faces.
Keywords: Autism Spectrum Disorder; amygdala reactivity; emotional processing; fMRI
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