Asthma Clinical Trial
Official title:
Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis
In this study will be consecutive enrolled children with asthma (classified according to
GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will
research clinical personal and parental history regarding allergic diseases, exposition to
passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick
Tests will be performed. In this study the investigators will evaluate lung function
parameters (spirometry with bronchial reversibility test and exercise induced
bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory
indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature,
nasal cytology.
The aim of the study will be to evaluate possible correlation between these different
parameters and clinical status of the patients.
Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy. ;
Observational Model: Case-Only, Time Perspective: Cross-Sectional
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