Clinical Trials Logo
  1. Home
  2. Arthroplasty Complications
  3. NCT03772535
  4. Details
NCT03772535 Clinical Trial

Pharmacogenetics for Pain Management in Joint Replacement Patients

Arthroplasty Complications Clinical Trial

— PGx  

Official title:
Using Pharmacogenetics to Structure Individual Pain Management Protocols for Joint Replacement Patients

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT03772535
Other study ID # AORI 2018-0100
Secondary ID
Status Enrolling by invitation
Phase Phase 3
First received
Last updated
Start date December 3, 2018
Est. completion date December 2021

Study information
Verified date February 2021
Source Anderson Orthopaedic Research Institute
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine the ability to use pharmacogenetic testing in a joint replacement practice to prescribe the most effective pain medicine for a specific patient.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 50
Est. completion date December 2021
Est. primary completion date June 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Primary total hip or total knee arthroplasty cases Exclusion Criteria: - History of narcotic dependence

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Pharmacogenomics Testing
The doctor will use genetic test results to prescribe medications that are a most effective for subject.

Locations
Country Name City State
United States Anderson Orthopaedic Research Institute Alexandria Virginia

Sponsors (1)
Lead Sponsor Collaborator
Anderson Orthopaedic Research Institute

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Genetic variants Percent of subject with genetic variants affecting pain medication 10 days postoperative
Secondary pain levels 0-10 subjective pain scale 10 days postoperatively
See also
  Status Clinical Trial Phase
Active, not recruiting NCT05181566 - Metal Ion Levels in Total Hip Arthroplasty (THA) With Modular Dual Mobility Cup Compared to Conventional THA N/A
Completed NCT04490304 - The Analysis of Posterior Soft Tissue Repair Durability N/A
Completed NCT05974501 - Pre vs Post Block in Total Knee Arthroplasty (TKA) Phase 4
Completed NCT04565093 - Efficacy of iPACK After Unilateral TKA N/A
Recruiting NCT05845021 - Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty N/A
Recruiting NCT03306810 - Recognition and Treatment of Dysglycemia. AGS - Acute Glucose Service N/A
Completed NCT04289025 - Modelling and AI Using Sensor Data to Personalise REHABilitation Following Joint Replacement N/A
Not yet recruiting NCT06469177 - Patient Centered Post-Op Pain Management Software Tool Interventional Study Verses Standard of Care N/A
Not yet recruiting NCT05014932 - Evaluation of Noise Induced by Ceramic-ceramic Friction Torques of Total Hip Prostheses With Customized Femoral Stem
Active, not recruiting NCT04437888 - Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty Early Phase 1
Completed NCT05420194 - Assessment of Postural Stability in Patients With Total Knee Arthroplasty
Completed NCT03269760 - Multimodal Sleep Pathway for Shoulder Arthroplasty Phase 1
Completed NCT03289247 - Tissue Adhaesive in Wound Closure Following Primary Total Knee Arthroplasty N/A
Completed NCT04433962 - Investigation of the Effects of Balance Training on Balance and Functional Status Patients With Total Hip Arthroplasty N/A
Recruiting NCT06025448 - Is MIO-RSA Noninferior to BIO-RSA When it Comes to Mechanical Implant Stability? N/A
Recruiting NCT05459259 - Physiotherapy for Arthrofibrosis Following Knee Replacement.
Not yet recruiting NCT05736666 - Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement N/A
Active, not recruiting NCT03692364 - Evaluation of Metal-on-conventional-polyethylene vs Ceramic-on-ceramic Articulating Surfaces in Total Hip Arthroplasty N/A
Completed NCT05013879 - Kinesiotape for Edema After Bilateral Total Knee Arthroplasty N/A
Completed NCT04120324 - Incidence of 30 Day Return to Hospital Following Same Day Discharge Total Hip Arthroplasty