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Clinical Trial Summary

Etiopathogenesis of Chronic inflammatory rheumatisms (CIR) includes genetic, autoimmune and environmental factors. Their impact on the quality of life is important, leading to a sometimes severe disability. Thus they are likely to affect female fertility through several mechanisms, including autoimmune since the association between immunity and fertility has already been demonstrated in other autoimmune diseases.

This study wants to evaluate and compare the birth rate between CIR and control group.


Clinical Trial Description

Data collection will be carried out using a questionnaire submitted to women in charge of the rheumatology department of the University Hospital of Toulouse and having agreed to participate:

- women with Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis or Chronic juvenile arthritis for the chronic inflammatory rheumatism group

- women with a mechanical rheumatic pathology for the control group

The primary endpoint was birth rate after spontaneous or induced pregnancy in patients who attempted to procreate, in the CIR group and in the control group. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03452735
Study type Observational
Source University Hospital, Toulouse
Contact Jean Parinaud, MD
Phone 5 67 77 11 02
Email parinaud.j@chu-toulouse.fr
Status Recruiting
Phase
Start date July 16, 2018
Completion date July 2019

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