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Arm Paralysis clinical trials

View clinical trials related to Arm Paralysis.

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NCT ID: NCT04798378 Recruiting - Stroke Clinical Trials

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

Start date: April 16, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one arm sufficient to perform daily activities. This study could lead to the development of a product that could allow people with arm weakness or arm paralysis to use the NuroSleeve and similar devices to improve arm health and independent function.

NCT ID: NCT04124172 Not yet recruiting - Stroke Clinical Trials

Efficacy and Safety of rTMS Plus Rehabilitation for the Improvement of the Upper Extremity in Stroke (ERES)

ERES
Start date: October 15, 2019
Phase: N/A
Study type: Interventional

The rehabilitation of the upper limb after a stroke is a challenge due to its complexity and the important cerebral representation of it, particularly of the hand. Repetitive transcranial magnetic stimulation (rTMS) is a tool that can broaden the effect of rehabilitation and thus appears to be observed in different studies performed in patients in chronic phase. However, there are little data on its usefulness before 6 months after the stroke. The variability in the presentation, the fact that it is a phase where the motor deficit of the upper limb coexists with other deficits and medical problems partly explain the lack of specific studies. The investigators present here a preliminary study on the efficacy of rTMS associated with the rehabilitation program of the paretic upper extremity due to a stroke in comparison with sham rTMS. Patients (with moderate to mild involvement) will be randomly distributed in the two study groups and will be evaluated both clinically and neurophysiologically before and after the sessions to try to demonstrate if there is a positive effect in a safe manner.

NCT ID: NCT03913286 Active, not recruiting - Stroke Clinical Trials

Neuromotor Prosthetic to Treat Stroke-Related Paresis

Cortimo
Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the research is to develop a new medical device prototype to restore functional movement of an arm made weak due to a chronic stroke

NCT ID: NCT03629275 Terminated - Ischemic Stroke Clinical Trials

Investigation of Neural Stem Cells in Ischemic Stroke

PISCES III
Start date: August 31, 2018
Phase: Phase 2
Study type: Interventional

A study of stereotactic, intracerebral injection of CTX0E03 neural stem cells into patients with moderate to moderately severe disability as a result of an ischemic stroke.

NCT ID: NCT02117635 Completed - Hemiparesis Clinical Trials

Pilot Investigation of Stem Cells in Stroke Phase II Efficacy

PISCES-II
Start date: June 2014
Phase: Phase 2
Study type: Interventional

The primary aim of this Phase II trial is to determine whether it is sufficiently likely that CTX DP treatment at a dose level of 20 million cells improves the recovery in the use of the paretic arm in acute stroke patients to justify a subsequent larger prospectively controlled study. This study will evaluate the safety and efficacy of intracerebral CTX DP at a dose level of 20 million cells in patients with paresis of an arm following an ischaemic middle cerebral artery (MCA) stoke. Eligible patients will have no useful function of the paretic arm a minimum of 28 days after the ischaemic stroke (a modified NIH Stroke Scale (NIHSS) Motor Arm Score of 2, 3 or 4 for the affected arm).