Androgenetic Alopecia Clinical Trial
Official title:
Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation
This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.
Strip harvesting technique, a conventional hair transplantation procedure, is widely used in
the treatment of androgenetic alopecia for more than half a century. It provides less
time-consuming, more feasible and more cost-effective comparing with follicular unit
extraction (FUE) technique. However, linear scar at the donor site is also introduced.
The latest method to fine the scar at the donor site was invented and known as 'Trichophytic
closure technique'. It can be done by trimming upper or lower wound edge for about 1
millimeter (as Fig.1) before wound closure. Then the linear scar will be less visible after
hair growth. Anyway, there is no exactly wound edge (upper, lower or both) that recommended
for the excellent cosmetic results without any severe side effects. Therefore, this study
was designed to determine which is the best trichophytic closure technique.
This research is a pilot, split-wound comparison study of trichophytic closure techniques
for donor site in hair transplantation.10 males, aged ≥ 25 years, who require strip
harvesting follicular unit transplantation in the treatment of androgenetic alopecia will be
enrolled. Preoperative and perioperative process will be conducted as standard procedure
except wound closure technique. Each incision wound of donor site will be equally divided
into 3 parts (marked with tattoos as Fig.2) and each part will be randomly treated with
different trichophytic closure techniques as below.
- The 1-millimetre trimming of upper edge of linear incision before wound closure
- The 1-millimetre trimming of lower edge of linear incision before wound closure
- The 0.5-millimetre trimming of both edge of linear incision before wound closure For
evaluation, we have planned to assess both cosmetic results and side effects as shown
in the table. ( Table 1 - image file ) After data collecting process, we have planned
to analyze the demographic data, rate of infection and other side effects in a
descriptive manner. However, the evaluation for cosmetic results will be analyzed by
paired t-test in the same technique at different follow up period and by one-way ANOVA
between each technique at the same follow up period.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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