Alzheimer's Disease Clinical Trial
Official title:
Contribution of Actigraphy and Recognition Video in Apathy Assessment of Alzheimer's Disease : Experimental Research
Neuropsychiatric symptoms form part of the clinical picture of Alzheimer's disease (AD) and
other dementias. Irrespective of the severity of the disease, the most frequently
encountered symptom is apathy. Apathy is increasingly diagnosed in patients with
neurological and psychiatric conditions. Apathy is a disorder of motivation, defined as "the
direction, intensity and persistence of goal-directed behaviour". Most of the current
descriptions acknowledge this point and consider apathy in terms of a lack of goal-directed
behaviour, cognition or emotion. The classical neuropsychiatric symptom assessments are
subjective structured interview-based, using input from the caregiver and/or the patient.
New technologies are likely to provide us with a more objective measure. An example is
ambulatory actigraphy, consisting of a piezoelectric accelerometer designed to record arm
movement in three dimensions.
The aim of the present study is to assess using actigraphy and video recording signal, AD
patients with (n = 15) and without (n = 15) apathy and control subjects (n = 5) during an
activity of daily living scenario .
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science
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