Effects of Hydrogen Gas Inhalation on Adults of Various Ages

Status Completed

Clinical Trial Summary

Herein, investigated the effects of 4 weeks of H2 gas inhalation on community-dwelling adults of various ages.

Clinical Trial Description

Molecular hydrogen (H2) is a versatile therapeutic agent. H2 gas inhalation is reportedly safe and has a positive impact on a range of illnesses, including Alzheimer's disease (AD). Herein, investigated the effects of 4 weeks of H2 gas inhalation on community-dwelling adults of various ages. Fifty-four participants including those dropped out (5%) were screened and enrolled. The selected participants were treated as a single group without randomization. Evaluated the association between total and differential white blood cell (WBC) counts and AD risk at individual levels after 4 weeks of H2 gas inhalation treatment. Furthermore, evaluation of dementia-related biomarkers such as beta-site APP cleaving enzyme 1 (BACE-1), amyloid beta (Aβ), brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor A (VEGF-A), T-tau, monocyte chemotactic protein-1 (MCP-1), and inflammatory cytokines (interleukin-6). ;

Study Design

Related Conditions & MeSH terms

Alzheimer Disease

Clinical Trial Details

NCT number	NCT05891938
Study type	Interventional
Source	Wonju Severance Christian Hospital
Contact
Status	Completed
Phase	N/A
Start date	January 1, 2023
Completion date	April 5, 2023

View Details

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