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Allergic Rhinitis clinical trials

View clinical trials related to Allergic Rhinitis.

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NCT ID: NCT04877678 Completed - Allergic Rhinitis Clinical Trials

Effects of Second-generation Antihistamine Bepotastine on Cough Outcomes in Cough Patients With Allergic Rhinitis

Start date: October 1, 2021
Phase: Phase 4
Study type: Interventional

This is a phase 4 study to evaluate the the efficacy of second generation antihistamine on cough outcomes in cough patients with allergic rhinitis.

NCT ID: NCT04872868 Completed - Allergic Rhinitis Clinical Trials

Long-term Effect of a 3-month Supplementation With Holo-BLG on House Dust Mite Induced Allergic Rhinoconjunctivitis

Start date: January 27, 2021
Phase:
Study type: Observational

The aim of the study is to investigate the long-term effect of a lozenge containing beta-lactoglobulin (BLG), iron, retinoic acid, zinc and polyphenols (holo-BLG) in people with allergic rhinoconjunctivitis caused by house dust mites and the associated symptoms (symptom type and severity) during exposure to house dust mites in an Allergen Exposure Chamber (AEC). In particular, the study aims to evaluate whether the improvements in symptoms of house dust mite-induced rhinoconjunctivitis observed after 3 months of supplementation with holo-BLG can still be detected 7 to 8 months after the last intake.

NCT ID: NCT04871256 Completed - Allergic Rhinitis Clinical Trials

Effects of Septorhinoplasty on Allergic Rhinitis

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Allergic rhinitis (AR) is a chronic inflammatory disease that affects almost 30% of adult population. Some patients associate septal deviation, main cause of chronic nasal obstruction, and AR. Current literature about AR treatment with septoplasty (STP) is still contradictory, because is thought that patients with AR are not able to appreciate improvement after surgery. Patients diagnosed with allergic rinitis and septal deviation were evaluated to determined life quality and airflow obstruction evolution after STP.

NCT ID: NCT04851860 Not yet recruiting - Allergic Rhinitis Clinical Trials

Effect of Sublingual Immunotherapy on Platlet factor4 Level in Children

Start date: April 12, 2021
Phase: Phase 3
Study type: Interventional

Better management and improving outcome of children with allergic rhinitis

NCT ID: NCT04815187 Recruiting - Allergic Rhinitis Clinical Trials

Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease

Start date: June 7, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate a previously FDA-approved medication that is known to help with allergy symptoms to see if it can decrease symptoms in patients with Meniere's Disease.

NCT ID: NCT04790487 Withdrawn - Allergic Rhinitis Clinical Trials

Chlorpheniramine Maleate Nasal Spray for Chronic Rhinitis

Start date: July 30, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Allergic rhinitis is defined as the symptoms of sneezing, nasal itching, airflow obstruction, and, mostly, clear nasal discharge caused by IgE-mediated reactions against inhaled allergens and involving mucosal inflammation driven by T cells (Th2) auxiliary type 2. pollens and molds, as well as allergens from perennial interiors, such as dust mites, pets, pests, and some molds. The pattern of dominant allergens depends on the geographic region and degree of urbanization, but the general prevalence of sensitization to allergens does not vary among census districts in the United States. This research proposes to study a separate antihistamine in a nasal spray. It is important to note that this antihistamine is available without prescription (OTC) and has been studied intranasal since the 1950s1

NCT ID: NCT04709575 Completed - Allergic Rhinitis Clinical Trials

Study to Assess the Efficacy of Anti-Bet v 1 Monoclonal Antibodies in Adults to Reduce Symptoms of Seasonal Allergic Rhinitis

Start date: January 14, 2021
Phase: Phase 3
Study type: Interventional

The primary objective is to assess the reduction of allergic symptoms as measured by combined symptom and medication score (CSMS) during birch pollen season after a single dose of REGN5713-5714-5715 versus placebo.

NCT ID: NCT04670653 Withdrawn - Allergic Rhinitis Clinical Trials

Efficacy and Safety of Magnólia Nasal Gel in the Treatment of Allergic Rhinitis

Start date: August 1, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Magnólia nasal gel in the treatment of moderate-severe persistent or moderate-severe intermittent allergic rhinitis.

NCT ID: NCT04648930 Completed - Allergic Rhinitis Clinical Trials

Special Drug Use Observational Study of Xolair in Patients With Severe to Most Severe Seasonal Allergic Rhinitis Aged ≥ 12 Years and < 18 Years Whose Symptoms Were Inadequately Controlled Despite to Conventional Therapies

Start date: January 27, 2021
Phase:
Study type: Observational

This was a multicenter, uncontrolled, open-label, special drug use study to investigate the safety and efficacy of Xolair by collecting data in its clinical setting in patients with severe to most severe seasonal allergic rhinitis aged ≥ 12 years and < 18 years whose symptoms were inadequately controlled despite to conventional therapies and used Xolair.

NCT ID: NCT04637425 Completed - Allergic Rhinitis Clinical Trials

Effect of Bacterial Lysate on Nasal Carriage of Staphylococcus Aureus

Start date: April 22, 2018
Phase: Phase 3
Study type: Interventional

This study assesses the effectiveness of Polyvalent Mechanical Bacterial Lysate (PMBL-Ismigen) in reducing nasal methicillin-resistant Staphylococcus aureus (MRSA) colony growth in children with pollen allergic rhinitis (AR) aged 5 to 17. Half of the participants received PMBL and the other half received a placebo.