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Clinical Trial Summary

This is a phase I, non-blinded, non-randomized, pilot trial for safety and efficacy of DBS for AUD. Patients who meet inclusion and exclusion criteria will be identified and recruited from the practices of Sunnybrook psychiatrists. Five (5) to ten (10) subjects will be enrolled and study duration for each patient will be of one (1) year. Our primary objective is to establish the safety of DBS in a patient population with treatment refractory AUD. In addition to demonstrating safety, our second primary objective will be to evaluate if DBS-targeted nucleus accumbens in alcoholism is efficacious in the treatment-refractory patients with AUD. This will be measured by various outcome measures that will include validated scales to assess addiction and craving behaviours.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03660124
Study type Interventional
Source Sunnybrook Health Sciences Centre
Contact
Status Active, not recruiting
Phase N/A
Start date May 25, 2018
Completion date December 25, 2024

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