Prevention and Reduction of Alcohol and Drug Problems in a Clinical Psychiatric Youth Population

Alcohol Abuse Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01595568
• Other study ID #: CER CHU Ste-Justine 3435
• Status: Recruiting
• Phase: N/A
• First received: May 3, 2012
• Last updated: July 18, 2012
• Start date: February 2012

Study information

• Verified date: July 2012
• Source: St. Justine's Hospital
• Contact: Eveline Perrier-Ménard, MD
• Phone: 514-345-4931
• Email: eveline.perrier-menard[@]umontreal.ca
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Interventional

Clinical Trial Summary

In adolescents, mental health problems are frequently associated with substance misuse, even considered a risk factor for alcohol abuse and dependence. This dual diagnosis tends to complicate the patient's treatment and prognosis by increasing, among others, substance use problems, reckless behaviours, relationships and school problems and suicidal thoughts. It is therefore critical to invest time and effort into developing an efficient approach to prevent and reduce substance use problems and offer these children a more global and optimal treatment.

A brief personality-targeted intervention was developed with students of Canadian and English high schools based on four personality factors known to be implicated in the vulnerability to adolescent alcohol misuse (Impulsivity, Anxiety Sensitivity, Negative Thinking and Sensation Seeking) (Conrod et al., 2006,2008, O'Leary-Barrett 2010).

By helping the adolescents to develop better adaptive behaviours, this cognitive-behavioural intervention proved to reduce binge drinking, quantity and frequency of use and substance use problems (Conrod et al., 2006,2011).

The purpose of this study is to assess the impact of this intervention if combined to a regular treatment in a youth psychiatric population.

60 patients aged 14-17 years of a Child and Adolescent psychiatric department will be screened for personality risk with self-report assessments including the Substance Use Risk Profile Scale. Participants will be randomly assigned to a personality matched cognitive-behavioural intervention or a no-intervention control.

The main outcome measures of this study are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. primary completion date: July 2012
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 14 Years to 17 Years

Eligibility

Inclusion Criteria:

• Motive for psychiatric consultation

• Able to provide consent from parent/guardian for participation in the study

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Alcohol Abuse
• Anxiety Disorder
• Anxiety Disorders
• Conduct Disorder
• Disease
• Drug Abuse
• Mood Disorder
• Mood Disorders

Intervention

Behavioral:
• Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
• Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
• Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
• Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator

Locations

Country	Name	City	State
Canada	CHU Ste-Justine	Montréal	Quebec

Sponsors (1)

Lead Sponsor	Collaborator
St. Justine's Hospital

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Binge drinking frequency		Baseline - 4months	No
Primary	Change in Drinking frequency		Baseline - 4 months	No
Primary	Change in Drinking quantity		Baseline - 4 months	No
Primary	Change in Drinking problems		Baseline - 4 months	No
Secondary	Change in Emotional and behavioural problems	Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, assessed using the Strengths and Difficulties Questionnaire, the Drinking Motives Questionnaire and the Brief Symptom Inventory.	Baseline - 4 months	No