Adult Periodontitis Clinical Trial
Official title:
Comparative Evaluation of Treatment Of Infrabony Defects With and Without 1.2% Rosuvastatin Gel: In-Vivo Study
Study aims to evaluate clinical and radiographic effectiveness of 1.2% Rosuvastatin gel in the treatment of Infrabony defects in chronic periodontitis patients.
Source from where the patients will be selected:
10 patients with chronic periodontitis having two or more infrabony defects will be selected
from the Outpatient section of Dept. of Periodontology, Dr. D. Y. Patil Dental College and
Hospital, Pimpri, Pune - 18.
A detailed clinical examination, case history and written consent will be obtained from all
the participants.
Before surgery, each patient will be given careful instructions regarding proper oral hygiene
measures. A full-mouth phase I therapy will be performed. A periodontal re-evaluation will be
performed after 4 to 6 weeks of phase 1 therapy to confirm the desired sites for the study.
The selected sites will be divided randomly by using a Sequentially numbered, opaque, sealed
envelopes (SNOSE) randomization into control and test sites. The control site will be treated
with Access Flap Surgery (AFS), whereas test sites will be treated with AFS and 1.2%
Rosuvastatin gel. Suitable antibiotics and analgesics will be prescribed along with
Chlorhexidine digluconate rinses (0.2%) twice daily for 14 days. Patients will be examined at
4 weeks, 3 and 6 month after surgery.
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