Clinical Trials Logo

Clinical Trial Summary

Initiated in January 2008, The PE-aWARE (Pulmonary Embolism WArsaw REgistry) is an on-going single-centre prospective observational study of patients with confirmed acute pulmonary embolism (APE). Extensive data on consecutive patients with pulmonary embolism is collected and stored. The main objective is to collect and provide information on patients' characteristics, management, and outcome with the purpose of decreasing mortality in APE, the occurrence of bleeding, and the frequency of thromboembolic recurrences. Moreover, the PE-aWARE registry serves as a basis for creating predictive scores for clinicians which aid patient management. The study endpoints comprise clinically recognized (and objectively confirmed) recurrences of PE, major and minor bleeding complications classified according to the International Society on Thrombosis and Haemostasis classification, need for cardiopulmonary resuscitation or catecholamines, and death.


Clinical Trial Description

The Pulmonary Embolism WArsaw REgistry (PE-aWARE) is an on-going prospective observational study of patients with confirmed acute pulmonary embolism (APE). Carried out since January 2008, the registry includes consecutive patients hospitalized at a single centre. The primary data recorded include details of each patient's clinical status, co-morbidities, the prescribed treatment, the results of additional studies (ie EKG, imaging studies), and the outcome. The study endpoints comprise clinically recognized (and objectively confirmed) recurrences of PE, major and minor bleeding complications classified according to the International Society on Thrombosis and Haemostasis classification, need for cardiopulmonary resuscitation or catecholamines, and death. Collecting the fore mentioned data allows for clinicians to better manage the diagnostic workup and treatment and thus facilitates the prevention of possible future complications in APE patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03916302
Study type Observational [Patient Registry]
Source Medical University of Warsaw
Contact Piotr Pruszczyk, Prof.
Phone 00 48 22 502 11 44
Email piotr.pruszczyk@wum.edu.pl
Status Recruiting
Phase
Start date January 1, 2008
Completion date December 31, 2028

See also
  Status Clinical Trial Phase
Completed NCT00519506 - A Phase II Study to Evaluate the Efficacy of ThromboView® in the Detection of Pulmonary Emboli Phase 2
Not yet recruiting NCT04110275 - Injection of Recombinant Human Tissue-type Plasminogen Activator Derivative for Acute Pulmonary Embolism(rPA) Phase 2
Completed NCT05318092 - Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism N/A
Not yet recruiting NCT06189313 - CLEANer Aspiration for Pulmonary Embolism N/A
Not yet recruiting NCT05792397 - TwiFlow Thrombectomy Catheter sYstem for Acute Pulmonary Embolism (Twi-TYPE Study) N/A
Completed NCT01604538 - Italian Pulmonary Embolism Registry - IPER N/A
Completed NCT03631810 - Contemporary Clinical Management Of Acute Pulmonary Embolism
Recruiting NCT03504007 - Registry of Patients Prescribed Anticoagulation
Completed NCT01513759 - Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy Phase 3
Completed NCT03108833 - A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism Phase 2
Completed NCT04037423 - European Database on Catheter-directed Treatment of Pulmonary Embolism.
Not yet recruiting NCT05469724 - Clinical Pulmonary Embolism
Completed NCT01014156 - Epoprostenol in Pulmonary Embolism Phase 4
Recruiting NCT06038630 - 129Xe MRI Cardiopulmonary Phase 2
Recruiting NCT06192199 - The Diagnostic Value of APTT/Fibrinogen Ratio in Pulmonary Embolism
Recruiting NCT04757129 - Changes of Cardiopulmonary Function After Thrombolysis in Patients With Pulmonary Embolism
Completed NCT03966079 - Thrombolysis Endovascular Treatment of Pulmonary Embolism Phase 3
Recruiting NCT06062329 - SYMPHONY-PE Study for Treatment of Pulmonary Embolism N/A
Not yet recruiting NCT04480892 - Fibrinolytic Deficit in Patients With Acute PE
Enrolling by invitation NCT04047784 - Pilot Study to Evaluate the Role of EBUS in the Diagnosis of Acute PE in Critically Ill Patients N/A