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Acute Myocardial Infarction clinical trials

View clinical trials related to Acute Myocardial Infarction.

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NCT ID: NCT02559596 Withdrawn - Stroke Clinical Trials

Reactivation of Varicella Zoster Virus and Risk of Vascular Disease

Start date: June 2015
Phase:
Study type: Observational

The purpose of this study is to investigate whether there is an association between stroke or heart attack and reactivation of varicella zoster virus, measured by antibody levels, using linked data from the Health Survey for England and secondary care.

NCT ID: NCT02164058 Withdrawn - Clinical trials for Acute Myocardial Infarction

TandemHeart to Reduce Infarct Size (TRIS Trial)

TRIS
Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if a device known as the TandemHeart® System (TandemHeart) can help limit heart damage and reduce serious complications after a certain type of heart attack (acute ST elevation anterior wall myocardial infarction [STEMI]) by evaluating the use of the TandemHeart system prior to a procedure called percutaneous coronary intervention (PCI)

NCT ID: NCT01991366 Withdrawn - Clinical trials for Acute Myocardial Infarction

Should Integrilin be an Integral Part of Adjunctive Therapy in Patients Undergoing Primary PCI for ST-Elevation MI?

Start date: October 2013
Phase:
Study type: Observational

The aim of this observational study is to evaluate the in hospital and 6 month outcomes of the use of Glycoprotein IIb/IIIa inhibitor eptifibatide as adjunctive therapy in patients undergoing primary Percutaneous Coronary Intervention for ST-elevation myocardial infarction in a large tertiary referral center. It is hypothesized that Glycoprotein IIb/IIIa inhibitor use during primary Percutaneous Coronary Intervention for ST-elevation myocardial infarction/ acute myocardial infarction is superior to unfractionated heparin alone or bivalirudin alone. Additionally, after propensity matching this superiority remains.

NCT ID: NCT01974128 Withdrawn - Clinical trials for Acute Myocardial Infarction

Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction

Acute MI
Start date: October 2014
Phase: N/A
Study type: Interventional

The intent of this clinical study is to answer the questions: 1) Is the proposed treatment safe? and 2) Is treatment effective in improving cardiac function and clinical outcomes?

NCT ID: NCT01901471 Withdrawn - Clinical trials for Acute Myocardial Infarction

Cyclosporine in Acute Myocardial Infarction Complicated by Cardiogenic Shock

CLOTILDE
Start date: September 2015
Phase: Phase 2
Study type: Interventional

The size of the acute myocardial infarction (AMI) is related to ischemia and injury induced by tissue reperfusion. These reperfusion's injuries can be reduced by injection of cyclosporin A (CsA) at the time of reperfusion. This post-conditioning reduces the final infarct size 20 to 40%. This has been demonstrated in STEMI patients non-complicated by cardiogenic shock. Early revascularization in the AMI complicated by cardiogenic shock improves short-term and long term survival by reducing the size of the myocardial infarction. The hypothesis of this study is that the administration of Cyclosporin A to these patients, in addition to mechanical reperfusion, is likely to reduce the severity of the multi-organ failure associated with the cardiogenic shock and improve clinical outcome.

NCT ID: NCT01678339 Withdrawn - Clinical trials for Acute Coronary Syndrome

Sicilian Administrative Data Base Study in Acute Coronary Syndrome Patients

HEALTH-DB ACS
Start date: September 2012
Phase: N/A
Study type: Observational

Thi is an observational, non interventional, cohort analysis by using administrative databases (drugs treatment, laboratory and diagnostic tests, specialist visits and hospitalizations) of Sicilia region to evaluate treatment patterns of patients after Acute Coronary Syndrome (ACS) event.

NCT ID: NCT01636180 Withdrawn - Clinical trials for Acute Myocardial Infarction

Effect of the Repeated Loading Dose of Clopidogrel and High Dose of Clopidogrel Continuous Therapy on the Platelet Aggregation Inhibition in Patients With Myocardial Infarction Undergoing Interventional Treatment.

REL-0609
Start date: March 2012
Phase: Phase 4
Study type: Interventional

REL-0609 trial's hypothesis is that repeated loading doses of clopidogrel (600 mg) administration in addition to high dose of clopidogrel continuous therapy (150 mg/day) results in higher inhibition of the platelets' aggregation in patients with myocardial infarction undergoing interventional treatment comparing to the standard therapy. Such treatment strategy will not cause increased risk of bleeding complications. In many trials treatment with to repeated loading doses of clopidogrel together with high dose of clopidogrel continuous therapy resulted in: MACE reduction, improvement of the long term therapy results, lower risk of ischemic complications. Currently, data regarding to the results of the above treatment are still limited.

NCT ID: NCT01311518 Withdrawn - Clinical trials for Acute Myocardial Infarction

A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction

Start date: July 2019
Phase: Phase 2
Study type: Interventional

The objective of this study is to evaluate the safety and tolerability of two active doses of RGN-352 (thymosin beta 4, Tβ4, Injectable Solution) in patients with acute myocardial infarction receiving percutaneous coronary intervention angioplasty with or without stent placement. Approximately 75 subjects will be randomized to receive one of two RGN-352 doses of 1200 mg, or 450 mg, or placebo, administered iv by iv push daily for the first 3 consecutive days and weekly for 4 more weeks.

NCT ID: NCT01120769 Withdrawn - Clinical trials for Acute Myocardial Infarction

Acetaminophen to Prevent Ischemic Oxidative Reperfusion Injury During Percutaneous Coronary Intervention for Acute Myocardial Infarction

APRIORI Pilot
Start date: July 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to test the hypothesis that acetaminophen will reduce lipid peroxidation and isoprostane formation during reperfusion after percutaneous revascularization for acute myocardial infarction.

NCT ID: NCT00907231 Withdrawn - Clinical trials for Acute Coronary Syndrome

Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department

ESTIMATE
Start date: February 2010
Phase: N/A
Study type: Observational

This is a multi-center study to assess the diagnostic accuracy of the Troponin I assay in the Biosite Triage Cardio3 Panel at the point-of-care (POC) in adults presenting to the emergency department with possible acute myocardial infarction (AMI).