Medication Adherence Clinical Trial
Official title:
HAART Adherence Among HIV-infected Persons and the Factors Affecting Treatment Adherence
The general objective of this study is to evaluate HAART adherence in Estonia and the factors affecting adherence; and the impact of an individual adherence enhancement counselling and treatment monitoring model (Advanced Adherence, AdvAdh), compared to the regular counselling received by HAART patients.
Specific HIV treatment - HAART (Highly Active Antiretroviral Therapy) can suppress HIV
replication and consequently preserve the functioning of immune system. HAART therapy is a
lifelong treatment with several different concomitantly administered oral medications.
According to studies, low adherence to treatment is directly related to patient's knowledge
and beliefs about HAART.
Studies have shown the success of different interventions increasing adherence to HAART, but
additional studies need to be carried out in order to determine the most effective
components of the interventions and the methods most suitable considering the local context,
that could be used in everyday work and with limited resources.
The first places to implement the activities directed at improving treatment adherence are
medical institutions, i.e. the departments of infectious diseases where HIV-positive
individuals receive HAART treatment.
The aims of the study are:
- to determine the rate of adherence to HAART and its associated factors;
- to conduct a small-scale intervention (randomised controlled) study implementing a
brief adherence counseling targeting persons receiving HAART.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label
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