Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to assess the safety and tolerability of itacitinib in combination with corticosteroids in Japanese subjects with Grades II to IV acute graft-versus-host disease (aGVHD).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03497273
Study type Interventional
Source Incyte Corporation
Contact Incyte Corporation Call Center (ex-US)
Phone +800 00027423
Email globalmedinfo@incyte.com
Status Recruiting
Phase Phase 1
Start date March 20, 2018
Completion date August 2019

See also
  Status Clinical Trial Phase
Recruiting NCT02241018 - MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD Phase 2/Phase 3
Terminated NCT02245412 - A Phase 2a Study of ALXN1007 in Subjects With Newly Diagnosed Acute GI GVHD Phase 2
Recruiting NCT02659657 - Prophylaxis Roles of IL-2 Treatment on Acute GVHD After Transplantation Phase 2
Recruiting NCT01903473 - Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD) Phase 2
Recruiting NCT02044185 - Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation N/A
Recruiting NCT01765634 - Mesenchymal Stem Cells for Treatment of Refractory Acute Graft-versus-host Disease Phase 2
Terminated NCT00282503 - Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease Phase 3
Recruiting NCT01521039 - Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease N/A
Not yet recruiting NCT03721965 - Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects Phase 1/Phase 2
Recruiting NCT02611180 - Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease N/A