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Clinical Trial Summary

This study is to test the feasibility and tolerability of the metoprolol optimal dosing pathway by observing the percentage of patients achieving target dose followed the pathway on ACS patients during hospitalization.


Clinical Trial Description

Acute coronary syndrome(ACS) is one of the main manifestations of cardiovascular disease and one of the main causes for hospitalization in adults.

Previous studies showed that β-receptor blockers can reduce ACS patients' cardiovascular risk in both acute phase and secondary prevention. We summarized the metoprolol optimal dosing pathway based on Chinese and foreign guidelines as well as Chinese clinical practice.

Primary endpoint is the percentage of patients achieving target dose at time of discharge.

Secondary endpoints are the mean HR & BP at discharge and during the follow up period of the Patients who have achieved target dose at discharge. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03413410
Study type Interventional
Source Chinese PLA General Hospital
Contact Dandan Li, MD
Phone +8613810545564
Email ldd301heart@qq.com
Status Recruiting
Phase N/A
Start date February 1, 2018
Completion date July 30, 2020

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