Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to compare in a randomized double blinded controlled trial the effect of heavy slow resistance exercises combined with ultrasound guided injections with local anesthetic with or without glucocorticosteroid in patients with achilles tendinopathy.


Clinical Trial Description

Achilles tendinopathy is a common and often longlasting condition especially in a sports population. The highest incidence is seen in sports involving running and jumping. As the primary treatment eccentric exercises is recommended and 60-90% will benefit by that. Other studies have shown equal effect of stretching exercises. In a new study heavy slow resistance exercises has proven effective in achilles tendinopathy and the best treatment in lig.patellae tendinopathy. Injection with glucocorticosteroid is often used in the daily clinic, though inflammation is rarely found. Fredberg 2004 found a good short term effect of glucocorticosteroid injection in an RCT, but no effect in the long term, which the investigators explained by an aggressive rehabilitation with running after a few days. Even though 60-90% will benefit from exercises in efficacy studies, a recent pragmatic effectiveness study by Weetke 2015 found that only 26% did benefit from training alone, but if supplemented by need with 1-3 injections of glucocorticosteroid 76% achieved excellent or good result. To our knowledge no randomized clinical trials have investigated the combined effect of training and injections. The hypothesis of this study is, that training and slowly progressive rehabilitation combined with glucocorticosteroid injections will have better effect than the same training and rehabilitation combined with injections of local anesthetic. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02580630
Study type Interventional
Source Bispebjerg Hospital
Contact
Status Completed
Phase Phase 4
Start date April 2016
Completion date December 20, 2020

See also
  Status Clinical Trial Phase
Recruiting NCT04221711 - Safety and Efficacy of Repetitive Peripheral Magnetic Stimulation in Patients With Achilles Tendinopathy N/A
Completed NCT06057779 - The Effect of Loading Speed and Intensity During Exercise on the Immediate Structural Changes in the Achilles Tendon N/A
Active, not recruiting NCT00835939 - Treatment for Achilles Tendinopathy Phase 2/Phase 3
Completed NCT04059146 - Tendinopathy Education on the Achilles N/A
Active, not recruiting NCT06030908 - Outcome After Surgical Reconstruction of the Achilles Tendon Insertion.
Recruiting NCT04423900 - Smart Phone-Based Application for Evaluation and Rehabilitation of HindFoot Pain N/A
Completed NCT04632979 - Backward Running on a Negative Slope as a Treatment for Achilles Tendinopathy in Runners N/A
Terminated NCT03264326 - Efficacy of BFR Training Combined With Eccentric Exercise as Assessed by SWE in Subjects With Chronic AT N/A
Not yet recruiting NCT06056440 - Efficacy of a Physical Rehabilitation Program Using Virtual Reality in Patients With Chronic Tendinopathy (Virtendon-Rehab) N/A
Completed NCT04941469 - Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot N/A
Completed NCT04376294 - Using of Extracorporeal Shockwave Therapy in Treatment Of Achilles Tendinopathy N/A
Recruiting NCT06172218 - AM for Refractory Achilles Tendinopathy N/A
Recruiting NCT05105269 - Managing Achilles Pain II
Completed NCT06297317 - Longitudinal Changes in Achilles Tendon and Medial Gastrocnemius Muscle Architecture During a 156-km Ultradistance Trail Running Event
Completed NCT03067545 - Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics N/A
Not yet recruiting NCT06100822 - Managing Chronic Tendon Pain by Metformin Phase 1
Recruiting NCT01583504 - High Volume Saline Injections for Achilles Tendinopathy N/A
Recruiting NCT04816188 - Heel Pain in Adolescents: A Pilot Study on the Effectiveness of Exercise Therapy and Activity Modification N/A
Completed NCT05125198 - Translation, Cultural Adaptation and Validation of Urdu Version of VISA-A Questionnaire
Recruiting NCT05592990 - A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy Phase 2