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Clinical Trial Summary

The aim of this study is to compare efficacy of POEM and pneumatic dilatation in treatment of achalasia cardia.

Clinical Trial Description

Achalasia is an esophageal motility disorder which involves smooth muscle of the esophagus and the lower esophageal sphincter (LES). Achalasia causes difficulty swallowing, regurgitation, and sometimes chest pain and weight loss. Endoscopic treatments of achalasia can be provided in the form of dilatation of the LES or cutting of muscle fibers (myotomy) of the esophagus and of the LES under endoscopic viewing. Dilatation in this trial is accomplished with rigiflex balloons and myotomy via Per Oral Endoscopic Myotomy (POEM). The effectiveness of treatment of achalasia using each method will be compared in this trial. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

NCT number NCT02025790
Study type Interventional
Source Asian Institute of Gastroenterology, India
Contact D Nageshwar Reddy, MD
Phone +914023378888
Status Recruiting
Phase N/A
Start date December 2013
Completion date December 2015

See also
  Status Clinical Trial Phase
Recruiting NCT03784365 - Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia Phase 3
Not yet recruiting NCT03186248 - Randomized Clinical Trial Comparing Short Versus Long Oesophageal Myotomy in POEM for Achalasia Cardia. N/A
Recruiting NCT03438838 - Randomised Trial Between LHM Alone Vs LHM With Anterior Fundoplication In Achalasia Cardia N/A