Abortion, Septic Clinical Trial
— APAOfficial title:
A Randomized Clinical Trial on the Use or Not of Antibiotics After Hospital Discharge in Septic Abortion.
Verified date | March 2007 |
Source | Hospital de Clinicas de Porto Alegre |
Contact | n/a |
Is FDA regulated | No |
Health authority | Brazil: Ministry of Health |
Study type | Interventional |
The use of antibiotics in post-partum infection has been abbreviated. After 48 hours of
clinical improvement, the patient is discharged from the hospital without antibiotics. No
trials has been found in cases of septic abortion.
The purpose of the present study is to verify the need of antibiotics after clinical
improvement in cases of septic abortion.
Status | Terminated |
Enrollment | 56 |
Est. completion date | December 2007 |
Est. primary completion date | November 2007 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 50 Years |
Eligibility |
Inclusion Criteria: - Patients admitted at the hospital with a diagnosis of infected abortion and about to be discharged from the hospital. - Use of intravenous antibiotics (gentamicin and clindamycin) - Improvement of the clinical conditions for at least 48 hours (no fever, eating and walking normally, reduced vaginal bleeding) Exclusion Criteria: - Unwilling to participate in the study. - Use of antibiotics previously within one week. - Presence of tubo-ovarian abscess. - Known allergy to doxycycline or metronidazole. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Brazil | Hospital de Clínias de Porto Alegre | Porto Alegre | Rio Grande do Sul |
Lead Sponsor | Collaborator |
---|---|
Hospital de Clinicas de Porto Alegre |
Brazil,
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Brasil.Ministério da Saúde. Abortamento infectado. In: Ministério da Saúde, ed. Urgências e emergências maternas: guia para diagnóstico e conduta em situações de risco de morte materna. 1 ed. Brasília: MS/FEBRASGO; 2000: 13-17.
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Savaris R. Abortamento. In: Freitas FM, Costa SMH, Lopes JG, eds. Rotinas em Obstetrícia. 5 ed. Porto Alegre: Artmed; 2006: 70-77.
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Turnquest MA, How HY, Cook CR, O'Rourke TP, Cureton AC, Spinnato JA, Brown HL. Chorioamnionitis: is continuation of antibiotic therapy necessary after cesarean section? Am J Obstet Gynecol. 1998 Nov;179(5):1261-6. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical cure defined as no fever, no abdominal pain or bleeding. | 10 days after hospital discharge | Yes |