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Abnormal Renal Function clinical trials

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NCT ID: NCT02944214 Not yet recruiting - Clinical trials for Chronic Kidney Disease

Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients

Start date: October 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether febuxostat and benzbromarone could protect renal function in chinese, and which one could be better.

NCT ID: NCT02478086 Completed - Malnutrition Clinical Trials

Effects of High vs. Standard Protein Intake in Newborn Extreme Premature

experimental
Start date: August 2012
Phase: Phase 2
Study type: Interventional

Introduction: The preterm newborn of extremely low birth weight (PNELW), endures adverse nutritional conditions to mimic intrauterine growth. It´s known that amino acids contribute to protein synthesis, but also intervene in weight gain. Most newborns receive amino acids throw parenteral nutrition at a doses of 3.5gr/k/day, that doses its unable to reach the birth weight when discharged, so the weight its below the 10th percentile, which rises the risk for presenting alterations in neurodevelopment. Objective: To compare a higher doses of parenteral amino acids vs. standard doses, expecting an increased weight gain in the high amino acid doses group, meanwhile following the renal function security profile Methods: A randomize, single blind clinical trial, carried on, in the Neonatology Service of Unidad Medica de Alta Especialidad Numero 48 of the Instituto Mexicano del Seguro Social, in the city of Leon, Mexico. Between the period of 1st August 2012 to 31 January 2013. A standard doses of amino acids was administered (3.5gr) to a control group and a high doses (4gr) to an experimental group. Weight, urea, creatinine and blood urea nitrogen (BUN) were measured weekly. In the study were included all preterm newborns (PN) weighting less than 1500 grs and with less than 32 weeks of gestational age that match all the inclusion criteria. Statics Analysis: descriptive statistics were calculates, also chi2 test and Fisher Exact test were applied to categorical variables, t-student test to continuous variables, and ANOVA in multiple groups.

NCT ID: NCT02338323 Completed - Clinical trials for Chronic Kidney Disease

Compare the Renal Protective Effects of Febuxostat and Benzbromarone

Start date: January 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether febuxostat and benzbromarone could protect renal function, and which one could be better.