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Abnormal Cytology clinical trials

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NCT ID: NCT02864121 Recruiting - Abnormal Cytology Clinical Trials

Oncogenous HPV DNA Integration (Intégration De l'ADN Des HPV Oncogènes)

IDAHO
Start date: December 2015
Phase: Phase 0
Study type: Interventional

High-risk human papillomavirus (HR-HPV) are involved in cervical cancer development. Integration of HR-HPV DNA in cellular genomes is considered as a major event in the cervical cancer development. The aim of this study is to validate the integration of the HPV-HR as an appropriate biomarker of the severity of precancerous lesions and progression of cervical lesions towards cervical cancer. HR-HPV integration status will be analyzed by Molecular Combing technology, which allows direct and high-resolution visualization of the integration of high-risk HPV genomes.