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Clinical Trial Summary

The aim of this study is to demonstrate the beneficial effects on gut microbiota composition and activity of the diary intake of insoluble fiber (extract from Aspergillus Niger) for three weeks. The first studies about the fiber have shown a favorable gut microbiota modulation and an improvement of metabolic parameters like LDL cholesterol. In addition to fecal measurements, several biomarkers of colic fermentation will be assessed: expired gases, PolyUnsaturated Fatty Acid, Short Chain Fatty Acid (SCFA) after a rich-fiber breakfast (= 15 grams) and a nutritional challenge test at lunch. The gastrointestinal tolerance of fiber intake and the intestinal transit modification will be also followed during all the study.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03773900
Study type Interventional
Source Hospices Civils de Lyon
Contact
Status Completed
Phase N/A
Start date November 7, 2018
Completion date June 6, 2019

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