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Abdominal Aortic Aneurysm, Ruptured clinical trials

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NCT ID: NCT03320408 Recruiting - Clinical trials for Abdominal Aortic Aneurysm

Predicting Aneurysm Growth and Rupture With Longitudinal Biomarkers

Start date: October 4, 2017
Study type: Observational [Patient Registry]

First aim: PARIS study The main aim of the current study is to determine the association between abdominal aortic aneurysm (AAA) progression and the evolution of proteases and cytokines levels.To achieve this aim, we will prospectively collect blood, aortic tissue, patient data, and imaging data. Aortic tissue will only be obtained when patients undergo conventional open repair. The other biomaterials will be collected during regular patient follow-up visits, with a maximum frequency of once per year. Second aim: Pearl AAA biobank For future research purposes, a new biobanking infrastructure will be created to collect and store additional blood and urine samples in a biobank. This biobank will be embedded within the infrastructure of the 'Parelsnoer Institute' (PSI) and will be called Pearl AAA. The Pearl AAA will be established in the extension of the PARIS study