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Abdominal Adhesions clinical trials

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NCT ID: NCT01594385 Completed - Abdominal Adhesions Clinical Trials

Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients

OASIT
Start date: April 2010
Phase: N/A
Study type: Interventional

The goal of this study is to test the effects of Seprafilm adhesion barrier on patients who are undergoing open abdomen damage control management for traumatic injuries when compared to no adhesion barrier use. Specifically, the researchers wish to study the effects of Seprafilm adhesion barrier on: - the number and intensity of adhesions, - whether there is any difference between treatment groups (Seprafilm vs. no Seprafilm) who go on to successful definitive abdominal closure, - rate of occurrence of secondary complications (such as abscesses) associated with short- and long-term beneficial effects of reducing adhesion formation,and - whether there is any difference between treatment groups regarding patient functional recovery.

NCT ID: NCT00962650 Completed - Abdominal Adhesions Clinical Trials

Natural Orifice Transgastric Endoscopic (NOTES) Transgastric Diagnostic Peritoneoscopy With Laparoscopic Assistance

NOTES
Start date: June 2009
Phase: N/A
Study type: Interventional

The study will document being able to successfully perform transgastric diagnostic peritoneoscopy (laparoscopic visualization) using a small collection of study surgical tools.

NCT ID: NCT00665730 Terminated - Abdominal Adhesions Clinical Trials

Evaluation of the Safety and Effectiveness of Sepraspray™ in Reducing Post-surgical Adhesions

Start date: July 2007
Phase: N/A
Study type: Interventional

This study will examine the safety and efficacy of Sepraspray in the following model of abdominal surgery: total proctocolectomy and pelvic pouch with diverting ileostomy via laparotomy to treat ulcerative colitis or familial polyposis. Adhesion formation will be evaluated laparoscopically at ileostomy take down. NOTE: A decision was made to terminate this study in June 2008 due to low enrollment.