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1-5 Brain Metastases From Non-Small Cell Lung Cancer clinical trials

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NCT ID: NCT01755624 Active, not recruiting - Clinical trials for 1-5 Brain Metastases From Non-Small Cell Lung Cancer

Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)

Start date: January 2013
Phase: Phase 2
Study type: Interventional

The study is a prospective, randomly controlled phase II trial, designed to test the efficacy, safety and neurocognitive outcomes of a medical device, the NovoTTF-100A, in the treatment of NSCLC patients with controlled systemic disease, following optimal standard local treatment for 1-5 brain metastases (BM). The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.